Results Autonomic reflex screening was performed on 57 (85%) of the 67 patients. Neurologic assessment included electromyography, nerve conduction studies, and autonomic reflex screening (using the quantitative sudomotor axon reflex test, adrenergic function testing, heart rate response to deep breathing, and the Valsalva ratio). Main Outcome Measures In patients in whom symptoms could be elicited, vascular function with and without symptoms was assessed by measurement of local skin temperature, laser Doppler flow, and transcutaneous oximetry. Interventions Testing nerve and vascular function in patients without symptoms present testing vascular function after provoking symptoms with exercise or by increasing ambient temperature. Patients Sixty-seven patients presenting with erythromelalgia at Mayo Clinic, Rochester, Minn, from 1999 through 2001. Objective To assess the frequency and type of vascular changes and neurologic abnormalities in patients with erythromelalgia.ĭesign Prospective study of patients with no spontaneous symptoms at the time of their visit and with provoked symptoms.
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